MS Sequencing: Part 1 – Mechanism of action of DMTs


Comment by Dr. Mark Freedman
NeuroSens survey on sequencing – Part 1

Over a dozen disease-modifying therapies (DMT) are now available to treat relapsing forms of multiple sclerosis (MS), providing clinicians with a wealth of choices for initiating and maintaining therapy. But what is the rational approach to selecting the most appropriate therapy in an individual patient throughout the treatment course?

It takes 30 seconds

* When initiating a DMT, how important a role does the drug’s mechanism of action play in your decision?

* Do you believe that specific immune mechanisms have greater importance at different stages of the disease course?

* With respect to a DMT’s mechanism of action, what is your goal when initiating treatment?

* When is a DMT’s mechanism of action most important to your clinical decision-making?

* When switching therapy, what role does a DMT’s mechanism of action play in your decision?

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