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The woes of neurology drug development: Eli Lilly

November 21, 2012

…The difficulties of developing new therapies for neurological disorders is well documented (see CNS drug development: a pipeline of problems, Neurosens, November 9, 2011). The most recent case in point: Eli Lilly, which has had a tough summer with two of its late-stage drugs. Subscribe to read more It takes 30 seconds or login using your email address Please enter the email address that you registered the newsletter with Continue…

Testing the new NIA-AA criteria for MCI

November 21, 2012

…A European group has examined the risk of progression to Alzheimer’s disease for the four MCI subgroups outlined in the National Institute on Aging-Alzheimer’s Association (NIA-AA) recommendations (Guo et al. Eur Arch Psychiatry Clin Neurosci 2012; epublished August 30, 2012). Subscribe to read more It takes 30 seconds or login using your email address Please enter the email address that you registered the newsletter with Continue…

GDS recommended for depression screening in PD

November 21, 2012

…logy 2012;78:998-1006). Subscribe to read more It takes 30 seconds or login using your email address Please enter the email address that you registered the newsletter with Continue…

FDA delays review of alemtuzumab

November 7, 2012

…as a treatment for MS. The RTF letter requires that Genzyme reorganize the data presented and resubmit its application. Although no new data are required, the RTF is expected to delay any approval of the drug in MS by at least six months. The drug is currently under review by the European Medicines Agency. Subscribe to read more It takes 30 seconds or login using your email address Please enter the email address that you registered the newsletter…

Botulinum toxin type A may be effective for trigeminal neuralgia

November 7, 2012

…About two-thirds of patients with trigeminal neuralgia (TN) may respond to injections of botulinum toxin type A (BTX-A), according to the results of a double-blind, placebo-controlled trial (Wu et al. Cephalalgia 2012;32:443-450). Subscribe to read more It takes 30 seconds or login using your email address Please enter the email address that you registered the newsletter with Continue…