Vitamin D a useful add-on treatment in MS
October 3, 2013…the BENEFIT trial (Kappos et al. Neurology 2006;67:1242-1249) of interferon-beta-1b in clinically isolated syndrome (CIS) (Ascherio et al. ECTRIMS 2013; abstract 96). Serum 25(OH)D data were available at 6 and 12 months for 334 of 468 patients. Subjects with higher 25(OH)D levels had less disease activity, a slower rate of progression and a longer time to conversion to MS. For patients with a 50 ng/L higher serum 25(OH)D level, the hazard ratio fo…