Variable vaccine efficacy against CoV-2 variants
May 11, 2021…tical COVID (Haas et al. Lancet 2021; epublished 5 May 2021; www.thelancet.com/action/showPdf?pii=S0140-6736%2821%2900947-8). The estimated prevalence of the UK variant (B.1.1.7) at the time of the study was 94.5% of samples, indicating that efficacy against the variant was comparable to what has been reported against the pandemic strain (D614G variant). The UK variant has been associated with a higher risk of mortality (hazard ratio 1.67) (Grint…