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Traumatic brain injury: no effect on AD phenotype

REPORT FROM THE AMERICAN ACADEMY OF NEUROLOGY (AAN) 63RD ANNUAL MEETING, HONOLULU, HAWAII, APRIL 9-16, 2011 – The possible link between Alzheimer’s disease and a history of traumatic brain injury is unclear (for a review see Jellinger KA. Curr Opin Neurol 2004; 17: 719-723). This issue was examined in a retrospective analysis of pathology data for the period 1997 to 2010 (Mehta et al. AAN 2011; abstract P07.244). Traumatic brain injury was define…

First report of increased risk of prostate cancer in PD

…studies have suggested that cancer risk is generally lower in PD patients compared to those without PD (11% vs. 14%), including a lower risk of prostate cancer (RR 0.74) (Driver et al. Cancer Epidemiol Biomarkers Prev 2007; 16: 1260-1265; free full text at http://cebp.aacrjournals.org/content/16/6/1260.long). The risk of certain cancers (e.g. melanoma) may be higher. Subscribe to read more It takes 30 seconds or login using your email address Ple…

Plasma clusterin a possible biomarker of AD severity

…OLULU, HAWAII, APRIL 9-16, 2011 – Clusterin (apoJ) is a heterodimeric protein that may play a role in amyloid plaque formation by acting as an extracellular chaperone (for a review see Thambisetty M. Biomark 2010; 4: 831-834; free full text at www.futuremedicine.com/doi/abs/10.2217/bmm.10.108). Subscribe to read more It takes 30 seconds or login using your email address Please enter the email address that you registered the newsletter with Continu…

Oral cladribine discontinued for MS

…Oral cladribine will not be marketed for multiple sclerosis and the drug will be pulled in countries where it has already received approval, according to an announcement from manufacturer Merck KGaA. Subscribe to read more It takes 30 seconds or login using your email address Please enter the email address that you registered the newsletter with Continue…

Image broadcasting: teleconferencing useful in schizophrenia

UPDATE ON SCHIZOPHRENIA – The advent of teleconferencing technology has enabled telepsychiatry programs to improve access to mental health services, notably in countries such as Canada and Australia (Doze et al. J Telemed Telecare 1999; 5: 38-46). But is this approach appropriate in managing patients with psychotic disorders? Subscribe to read more It takes 30 seconds or login using your email address Please enter the email address that you regis…