…with antibody testing. Reverse-transcription polymerase chain reaction (RT-PCR) testing of blood, urine or saliva may be employed (Gourinat et al. Emerg Infect Dis 2015;21:84-86. Musso et al. J Clin Virol 2015;68:53-55). Zika is described as an Arbovirus, one of a variety of predominantly RNA viruses transmitted by mosquitoes and ticks. The main vectors are Aedes africanus and Ae. aegypti, but other Aedes species (e.g. Ae. albopictus, Ae. hensill…

…brain injury (Tchantchou et al. Neuropharmacology 2014;85:427-439). A first-in-human study of BIA 10-2474 was launched on July 9, 2015, with a planned enrolment of 128 healthy volunteers (90 on active drug, 38 on placebo). Following single-dose testing, multiple-dose testing was initiated in the first week of January 2016. The first adverse reactions were observed on January 10, when a subject presented with severe neurological symptoms that were…