New FDA warning for Tysabri
April 28, 2010…the newsletter with Continue…
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Chronic cerebrospinal venous insufficiency (CCSVI)
February 16, 2010View commentary by Daniel Selchen, MD Following news reports last fall of a possible cure for MS, clinicians and MS Societies worldwide have been inundated with inquiries about the new procedure. Its originator, Dr. Paulo Zamboni of Ferrara, Italy, has reported that a condition that he calls chronic cerebrospinal venous insufficiency (CCSVI) is the underlying problem in multiple sclerosis. Subscribe to read more It takes 30 seconds or login using…
Consensus statement: aripiprazole for acute mania
February 2, 2010A group in the U.K. has published a consensus statement on the use of the atypical antipsychotic aripiprazole for acute mania (Aitchison et al. J Psychopharmacol 2009; 23: 231-240). Unlike other atypical antipsychotic agents (clozapine, risperidone, olanzapine, quetiapine, ziprasidone), aripiprazole acts as a partial agonist at the dopamine D2 and serotonin 5HT-1A and 5HT-2C receptors, and as a 5HT-2A antagonist (for a recent review see Pae CU. E…
Milnacipran in major depression: meta-analysis
December 1, 2009…Milnacipran is a dual serotonin-norepinephrine reuptake inhibitor (SNRI) in use in Europe, Asia and Australia. Its norepineprine:serotonin effects are 3:1, in contrast to other SNRIs (e.g. venlafaxine, with a 1:30 norepineprine:serotonin ratio). Subscribe to read more It takes 30 seconds or login using your email address Please enter the email address that you registered the newsletter with Continue…
One-third of early PD patients show cognitive decline
October 20, 2009…A longitudinal study has examined cognitive decline in 106 patients with early Parkinsons disease (mean age 61.2 years). Cognitive decline was assessed using the Mini Mental State Examination (MMSE; mean baseline 27.8) (Kandiah et al. Mov Disord 2009); epublished February 3, 2009. Subscribe to read more It takes 30 seconds or login using your email address Please enter the email address that you registered the newsletter with Continue…