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Pilot study of adjunctive L-lysine in schizophrenia

June 8, 2011

…jgin et al. Neuropsychopharmacology 2008; 33: 1874-1883; free full text at www.nature.com/npp/journal/v33/n8/full/1301587a.html). For example, in the phenylcyclidine model of schizophrenia, PCP-induced behavioural effects appear to be due in part to an increase in NO activity (Klamer et al. Eur Neuropsychopharmacol 2005; 15: 587-590; Johansson et al. Psychopharmacology (Berl); 1997; 131: 167-173). Subscribe to read more It takes 30 seconds or logi…

Positive symptoms common in non-converters to psychosis

May 25, 2011

…(NAPLS) is an ongoing collaborative research project by a consortium of research centres, including the University of Toronto. [For the background see Addington et al. Schizophr Bull 2007; 33: 665-672; free full text at www.ncbi.nlm.nih.gov/pmc/articles/PMC2526151/?tool=pubmed.] Subscribe to read more It takes 30 seconds or login using your email address Please enter the email address that you registered the newsletter with Continue…

Comorbidities common, delay MS diagnosis

April 15, 2011

…63rd ANNUAL MEETING OF THE AMERICAN ACADEMY OF NEUROLOGY (AAN), HONOLULU, HAWAII, APRIL 9-16, 2011 – The U.S. National Health and Wellness Survey, an annual internet survey of health behaviours, reports that people with MS more commonly report comorbidities compared to those in the general population (Meletiche et al. AAN 2011; abstract P06.045). Subscribe to read more It takes 30 seconds or login using your email address Please enter the email ad…

Alemtuzumab reduces 1-year sustained disability: CAMS223 analysis

April 14, 2011

…Y (AAN), HONOLULU, HAWAII, APRIL 9-16, 2011 – CAMMS23 was a phase II trial comparing alemtuzumab, a monoclonal antibody that targets CD52 lymphocytes, with subcutaneous beta-interferon-1a (CAMMS223 Trial Investigators et al. N Engl J Med 2008; 359: 1786-1801; free full text at www.nejm.org/doi/full/10.1056/NEJMoa0802670). Alemtuzumab dosing groups received either 12 or 24 mg IV x 1 cycle/year. While alemtuzumab appeared to be more effective than b…