FDA approves ozanimod in MS
April 16, 2020…in tyramine (e.g. aged cheese, cured/smoked meats and fish, fava beans). Co-administration of ozanimod with MAO-A or MAO-B inhibitors (e.g. phenelzine, selegiline) is contraindicated. Concomitant use of serotonergic drugs (e.g. SSRIs, SNRIs, tricyclic antidepressants) is not recommended. The monograph notes that there may be a risk of severe side effects in patients taking opioids. There are also significant drug-drug interactions with CYP2C8 indu…