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What is the optimal dosing of natalizumab?

REPORT FROM THE AMERICAN ACADEMY OF NEUROLOGY (AAN) ANNUAL MEETING, NEW ORLEANS LA, APRIL 21-28, 2012 – The initial dose-ranging study of natalizumab indicated that 1-3 mg/kg was clinically effective (Sheremata et al. Neurology 1999;52:1072-1074) and this was the dose selected by the Natalizumab MS Trial Group (O’Connor et al. Neurology 2004;62:2038-2043). Subscribe to read more It takes 30 seconds or login using your email address Please enter t…

New AAN guidelines for migraine prophylaxis

…e AAN annual meeting coincided with the publication of new guidelines on preventive treatment of migraine by the AAN and the American Headache Society (Silberstein et al. Neurology 2012;78:1337-1345; free full text at www.neurology.org/content/78/17/1337.full.pdf+html). Subscribe to read more It takes 30 seconds or login using your email address Please enter the email address that you registered the newsletter with Continue…

Flunarizine, topiramate effective in migraine prophylaxis

…A one-year study reports that topiramate and flunarizine are both effective in migraine prophylaxis, although combining the two agents does not produce significantly greater efficacy (Luo et al. Pain Med 2012;13:80-86). Subscribe to read more It takes 30 seconds or login using your email address Please enter the email address that you registered the newsletter with Continue…

Internet-based CBT an option for social anxiety disorder

…ral therapy (CBT) administered via the Internet was as effective as conventional cognitive-behavioural group therapy (CBGT) in the treatment of social anxiety disorder (Hedman et al. PLoS One 2011;6:e18001; free full text at www.ncbi.nlm.nih.gov/pmc/articles/PMC3070741/pdf/pone.0018001.pdf). Subscribe to read more It takes 30 seconds or login using your email address Please enter the email address that you registered the newsletter with Continue…