…many, September 9-12, 2009 A majority of patients in the placebo arm of MS treatment trials report nocebo reactions, defined as the development of nonspecific adverse effects following administration of a placebo (Kennedy WP. Med World 1961; 95: 203-205), according to an analysis of 60 trials of disease-modifying drugs (Papadopoulos & Mitsikostas. ECTRIMS 2009). Subscribe to read more It takes 30 seconds or login using your email address Please en…

…of the MECOMBIN trial of pulsed methylprednisolone plus intramuscular beta-interferon-1a indicate that the combination is not more effective in delaying the onset of disability progression, although improvements in relapse rate and functional scores were observed (Ravnborg et al. ECTRIMS 2009). Subscribe to read more It takes 30 seconds or login using your email address Please enter the email address that you registered the newsletter with Contin…

…er 9-12, 2009 Teriflunomide is an immunosuppressant currently being tested in four large phase III trials in clinically isolated syndrome (estimated enrollment 780), MS with relapses (TEMSO trial, estimated n=1080), relapsing-remitting MS (planned n=1110) and versus beta-interferon-1a in RRMS (TENERE trial, estimated n=300). The drug is the active metabolite of leflunomide that is used in the treatment of rheumatoid arthritis. Subscribe to read mo…

…REPORT FROM THE 25th CONGRESS OF THE ECTRIMS – Dusseldorf, Germany, September 9-12, 2009 In 2008, the MS Study Group of the Italian Neurological Society reported that one-third of children/adolescents with MS demonstrated cognitive impairments (Amato et al. Neurology 2008; 70: 1891-1897). Subscribe to read more It takes 30 seconds or login using your email address Please enter the email address that you registered the newsletter with Continue…