An estimated 5-7% of patients experience seizures following traumatic brain injury (TBI). Current guidelines by the Brain Trauma Foundation and the AAN recommend the use of anti-seizure medications limited to the first seven days post-trauma (Brain Trauma Foundation. J Neurotrauma 2007;24(suppl 1); free full supplement at www.braintrauma.org/pdf/protected/Guidelines_Management_2007w_bookmarks.pdf).
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Inappropriate prescribing common in AD patients
November 13, 2013Three European studies have reported that elderly patients – notably those with Alzheimer’s disease – are highly likely to receive inappropriately prescribed medications both in the community and in the nursing home setting.
Increased risk of relapse with risperidone discontinuation in AD
October 23, 2013A randomized, double-blind study has examined the risk of relapse in AD patients with psychosis or agitation/aggression when the atypical antipsychotic risperidone was withdrawn (Devanand et al. N Engl J Med 2012;367:1497-1507).
Recurrent depression in the community: NEMESIS results
October 23, 2013Data obtained from the Netherlands Mental Health Survey and Incidence Study (NEMESIS) indicate a high risk of recurrence among patients treated for major depression (Hardeveld et al. Psychol Med 2013;43:39-48). The study included 687 subjects with major depressive disorder (DSM-III-R) in remission for at least six months and prospectively followed-up for three years.