Dietary salt may worsen MS


REPORT FROM THE ACTRIMS-ECTRIMS – BOSTON, MA, SEPTEMBER 10-13, 2014 – Recent studies have indicated that increased sodium chloride concentrations can induce pathogenic CD4+ Th17 cells in humans (Kleinewietfeld et al. Nature 2013;496:518-522; free full text at This effect is specific to Th17, with little or no effect on Th1 or Th2 differentiation or proliferation. Moreover, salt-induced Th17 cells demonstrate increased production of pro-inflammatory cytokines, such as TNF-alpha and IL-2.

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