A case-control analysis of data from the Physicians’ Health Study reports that there is insufficient evidence that NSAID use lowers the risk of Parkinson’s disease (Driver et al. Br Med J 2011; epublished January 20, 2011; free full text at www.bmj.com/content/342/bmj.d198.long). The database included 22,007 physicians aged 40-84 years. Cases were matched by age and confounders (comorbidity, indicators for NSAID use).