Anti-LINGO-1 MAb in optic neuritis: RENEW results

 

REPORT FROM THE 67TH AMERICAN ACADEMY OF NEUROLOGY (AAN) ANNUAL MEETING – WASHINGTON DC, APRIL 18-25, 2015 – BIIB033 is a monoclonal antibody targeting LINGO-1 (leucine-rich repeat and immunoglobulin domain-containing neurite outgrowth inhibitor receptor-interacting protein-1), which is expressed on neurons and oligodendrocytes and which impedes oligodendrocyte differentiation and myelination.

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